asthma exacerbation treatment
Asthma: treatment of exacerbationsAsthma: Treatment of exacerbations
Author links open overlay panelM.LubretaJ.-F.BervarbC.ThumerelleaA.DeschildreaI.Tillie-Leblondb
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Introduction
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| asthma |
State of knowledge
The evaluation of the initial gravity, based on the concept of risky terrain and clinical examination, will guide the choice of treatment and reception facilities. The treatment is based on bronchodilators and corticosteroids in the majority of cases.
prospect
An episode of exacerbation may be an opportunity to establish contact with the patient (educational approach) to increase adherence to treatment with inhaled corticosteroids, which remains the best preventive management of future exacerbation.
Conclusion
Early and appropriate management of episodes of exacerbation of asthma should reduce morbidity and mortality. It could also improve the socio-economic cost of these episodes by reducing the number and duration of hospitalizations.
Summary
Introduction
Exacerbations remain, in both adults and children, at common reason for emergency consultation. The management of the asthmatic patient with an acute exacerbation is well defined.
background
The initial evaluation, based on the risk factors and the clinical examination, will determine the choice of treatment and management. Treatment is based on bronchodilators and corticosteroids in the majority of cases.
Viewpoints
An episode of exacerbation may be the opportunity to establish contact with the patient (an educational approach) to improve adherence to long-term treatment with inhaled corticosteroids, which will remain the best way of preventing future exacerbations.
Conclusion
Early and appropriate management of asthma exacerbations should reduce asthma morbidity and mortality. It could also reduce the socioeconomic costs of these episodes and the duration of hospital admissions.
Epidemiology and Risk Factors of Venous ThromboembolismEpidemiology and Risk Factors of Venous Thromboembolism
Author links open overlay panelA.DellucabcF.The VenabcD.MottierabcG.The Galabc
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Introduction
Venous thromboembolism (VTE) is a common pathology whose incidence increases with age. In subjects over 75 years old, its incidence reaches one case per 100 people per year.
State of knowledge
Apart from major risk circumstances (surgery, trauma, acute medical conditions), four risk factors modify the management of VTE in any context, and are particularly important to consider: age, cancer, history of VTE, pregnancy. Biologically, apart from the antiphospholipid syndrome and some antithrombin deficits, thrombophilias are not of major clinical interest in the management of VTE.
prospect
"Thrombophilias" are great tools for understanding VTE, and the search for new biological abnormalities and the study of their impact must continue. The recent demonstration of the links between MVTE and arterial pathology, in particular atherothrombotic, brings out the concept of disease and global vascular prevention.
conclusions
VTE is a major public health problem. It appears necessary to know the risk factors and identify high-risk patients to limit its incidence and mortality.
Summary
Introduction
Venous thromboembolism (VTE) is a common disease. The incidence of rises markedly with increasing age; over the age of 75, the annual incidence reaches 1 per 100.
background
In addition, VTE: increasing age, cancer, previous history of VTE and pregnancy. To date, with the exception of the antiphospholipid syndrome and antithrombin deficiency, "thrombophilias" do not appear to change the management of VTE.
Viewpoints
Thrombophilias are useful tools for understanding the pathophysiology of VTE. Therefore, further studies are needed to identify new biological abnormalities and their impact on the risk of VTE. Recently, links between VTE and atherosclerosis have been demonstrated, leading to new concept of pan-vascular disease and prevention.
conclusions
VTE is a major public health problem. The knowledge of VTE risk factors is of major importance in identifying high-risk patients and in reducing the incidence and mortality of VTE.
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